The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants
Author:
Affiliation:
1. Matière et Systèmes Complexes
2. UMR 7057 CNRS Université Denis Diderot Paris-VII
3. Bâtiment Condorcet
4. 75205 Paris
5. France
Abstract
Inhaled nanoparticles reaching the respiratory zone in the lungs enter first in contact with the pulmonary surfactant. It is shown here that nanoparticles and lipid vesicles formulated from different surfactant mimetics interact predominantlyviaelectrostatic charge mediated attraction and do not form supported lipid bilayers spontaneously.
Funder
Agence Nationale de la Recherche
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/SM/C8SM00925B
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