Identification and characterization of enzymes involved in the biosynthesis of pyrimidine nucleoside antibiotics-Reference-Cited by-同舟云学术

Identification and characterization of enzymes involved in the biosynthesis of pyrimidine nucleoside antibiotics

Published:2021 Issue:7 Volume:38 Page:1362-1407
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

McErlean M.¹²³⁴,Liu X.¹²³⁴,Cui Z.¹²³⁴,Gust B.⁵⁶⁷⁸,Van Lanen S. G.¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Science

2. College of Pharmacy

3. University of Kentucky

4. USA

5. Pharmaceutical Institute

6. Department of Pharmaceutical Biology

7. University of Tübingen

8. Germany

Abstract

This review highlights the functional assignment and partial characterization of multiple proteins involved in the biosynthesis of structurally complex pyrimidine-derived nucleoside antibiotics.

Funder

National Cancer Institute

National Institute of Allergy and Infectious Diseases

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NP/D0NP00064G

Reference312 articles.

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5. Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. III. Microbiologic profile.

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