Impact of N-heteroaromatic N-termini in Cu(<scp>ii</scp>) ATCUN metallopeptides on their biorelevant redox activity-Reference-Cited by-同舟云学术

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Impact of N-heteroaromatic N-termini in Cu(ii) ATCUN metallopeptides on their biorelevant redox activity

Published:2023 Issue:11 Volume:52 Page:3279-3286
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Barrera Jannis¹²,H. Haeri Haleh³,Heinrich Julian¹,Stein Matthias⁴^ORCID,Hinderberger Dariush³^ORCID,Kulak Nora¹^ORCID

Affiliation:

1. Institute of Chemistry, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany

2. Department of Chemistry, Humboldt-Universität zu Berlin, Brook-Taylor-Strasse 2, 12489 Berlin, Germany

3. Institute of Chemistry, Martin-Luther-Universität Halle-Wittenberg, Von-Danckelmann-Platz 4, 06120 Halle, Germany

4. Max Planck Institute for Dynamics of Complex Technical Systems, Molecular Simulations and Design Group, Sandtorstrasse 1, 39106 Magdeburg, Germany

Abstract

Incorporation of artificial N-donor molecules into Cu(ii) ATCUN peptides leads to efficient ROS generation and oxidative DNA degradation.

Funder

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D2DT02044K

Reference45 articles.

1. Advances in Copper Complexes as Anticancer Agents

2. Copper complexes as artificial DNA metallonucleases: From Sigman’s reagent to next generation anti-cancer agent?

3. Copper complexes as therapeutic agents

4. Copper Compounds in Anticancer Strategies

5. Copper-binding Properties of Bovine Serum Albumin and Its Amino-terminal Peptide Fragment

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1. Chemical accuracy for ligand-receptor binding Gibbs energies through multi-level SQM/QM calculations;Physical Chemistry Chemical Physics;2024

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