Asymmetric formal synthesis of (−)-tetrazomine
Author:
Affiliation:
1. School of Biotechnology and Health Sciences
2. Wuyi University
3. Jiangmen
4. China
5. International Healthcare Innovation Institute(Jiangmen)
6. Department of Chemistry
7. Zhejiang University
8. Hangzhou
9. 310027 China
Abstract
The asymmetric formal synthesis of (−)-tetrazomine, a structurally unique member of the tetrahydroisoquinoline alkaloids, is presented.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00029B
Reference58 articles.
1. Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
2. Recent progress in the total synthesis of naphthyridinomycin and lemonomycin tetrahydroisoquinoline antitumor antibiotics (TAAs)
3. Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics
4. Progress in the Synthesis of Analogues of Bistetrahdro-isoquinoline Antitumor Alkaloids
5. Tetrazomine, a new antibiotic produced by an actinomycete strain. Taxonomy, fermentation, isolation and characterization.
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