Microengineered cultures containing human hepatic stellate cells and hepatocytes for drug development

Author:

Davidson Matthew D.12345ORCID,Kukla David A.5674,Khetani Salman R.12345ORCID

Affiliation:

1. School of Biomedical Engineering

2. Colorado State University

3. Fort Collins

4. USA

5. Department of Bioengineering

6. University of Illinois at Chicago

7. 218 SEO Chicago

Abstract

Micropatterned tri-cultures (MPTCs) containing human hepatocytes, hepatic stellate cells, and fibroblasts in a high-throughput format are used to mimic aspects of non-alcoholic steatohepatitis (NASH) for drug screening.

Funder

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

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