Quantifying 3D chemotaxis in microfluidic-based chips with step gradients of collagen hydrogel concentrations-Reference-Cited by-同舟云学术

Quantifying 3D chemotaxis in microfluidic-based chips with step gradients of collagen hydrogel concentrations

Published:2017 Issue:4 Volume:9 Page:339-349
ISSN:1757-9694
Container-title:Integrative Biology
language:en
Short-container-title:Integr. Biol.

Author:

Del Amo C.¹²³⁴⁵,Borau C.¹²³⁴⁵,Movilla N.¹²³⁴⁵,Asín Jesús⁶³⁴⁵,García-Aznar J. M.¹²³⁴⁵^ORCID

Affiliation:

1. Aragón Institute of Engineering Research (I3A)

2. Department of Mechanical Engineering

3. University of Zaragoza

4. Zaragoza

5. Spain

6. Department of Statistical Methods

Abstract

In this work a microfluidic chip is proposed, consisting of three different channels for studying cell migration under chemical and mechanical gradients such as collagen concentrations of matrices and growth factors.

Funder

European Research Council

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://pubs.rsc.org/en/content/articlepdf/2017/IB/C7IB00022G

Reference59 articles.

1. A microfluidic Transwell to study chemotaxis

2. Visualizing Cancer Cell Chemotaxis and Invasion in 2D and 3D

3. Measuring Chemotaxis Using Direct Visualization Microscope Chambers

4. Cell migration and invasion assays

5. Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform

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