QSAR modeling for predicting reproductive toxicity of chemicals in rats for regulatory purposes
Author:
Affiliation:
1. ETRC
2. Lucknow-226 010
3. India
4. Environmental Chemistry Division
5. CSIR-Indian Institute of Toxicology Research
6. Lucknow-226 001
Abstract
The figure shows the prediction performance of (a) DTF-QSAR and (b) DTB-QSAR models for pLOAEL (rat) in training and test data.
Publisher
Oxford University Press (OUP)
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://pubs.rsc.org/en/content/articlepdf/2016/TX/C6TX00083E
Reference56 articles.
1. QSAR models for reproductive toxicity and endocrine disruption in regulatory use – a preliminary investigation
2. National Toxicology Programme, Prenatal Developmental Toxicity Study, available at: https://ntp.niehs.nih.gov/testing/types/dev/
3. Predictive Model of Rat Reproductive Toxicity from ToxCast High Throughput Screening1
4. Profiling the Reproductive Toxicity of Chemicals from Multigeneration Studies in the Toxicity Reference Database
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