Thioacids – synthons for amide bond formation and ligation reactions: assembly of peptides and peptidomimetics
Author:
Affiliation:
1. Department of Chemistry
2. University College of Science
3. Tumkur University
4. Tumkur 572 103
5. India
6. Room No. 109
7. Peptide Research Laboratory
8. Department of Studies in Chemistry
9. Central College Campus
10. Dr B. R. Ambedkar Veedhi
Abstract
The synthesis of α-amino thioacids and peptide thioacids and their applications in chemoselective amide bond formation, ligation of peptides/proteins/glycopeptides and synthesis of peptidomimetics are reviewed.
Funder
Science and Engineering Research Board
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00512E
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