Synthesis and antiproliferative activity of benzimidazole-based, trinuclear neutral cyclometallated and cationic, N^N-chelated ruthenium(ii) complexes

Author:

Welsh Athi1234ORCID,Rylands Laa-iqa1234,Arion Vladimir B.567ORCID,Prince Sharon8294,Smith Gregory S.1234ORCID

Affiliation:

1. Department of Chemistry

2. University of Cape Town

3. Cape Town

4. South Africa

5. Institute of Inorganic Chemistry of the University of Vienna

6. 1090 Vienna

7. Austria

8. Department of Human Biology

9. Faculty of Health Science

Abstract

A series of 2-phenyl and 2-pyridyl tris-benzimidazole ligands was reacted with the [Ru(p-cymene)Cl2]2 dimer to yield the corresponding neutral cyclometallated and cationic trinuclear organoruthenium(ii) complexes.

Funder

University of Cape Town

National Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference56 articles.

1. R. W. Ruddon , Cancer Biology , Oxford University Press , 4th edn, 2007

2. CANSA , CANSA: Statistics, http://www.cansa.org.za/files/2016/08/Fact-Sheet-Cancer-NCR-2011-web-Aug-2016.pdf

3. WHO , WHO: Cancer, http://www.who.int/mediacentre/factsheets/fs297/en/

4. Treating metastatic cancer with nanotechnology

5. M. Gaba and C.Mohan , Development of drugs based on imidazole and benzimidazole bioactive heterocycles: Recent advances and future directions , Springer US , 25th edn, 2016

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