Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties-Reference-Cited by-同舟云学术

Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties

Published:2021 Issue:7 Volume:12 Page:1154-1163
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

de Andrade Ramos Giselle¹²³⁴⁵,Souza de Oliveira Andressa¹²³⁴⁵,Bartolini Manuela⁶⁷⁸⁹,Naldi Marina⁶⁷⁸⁹,Liparulo Irene⁶⁷⁸⁹,Bergamini Christian⁶⁷⁸⁹,Uliassi Elisa⁶⁷⁸⁹^ORCID,Wu Ling¹⁰¹¹¹²¹³,Fraser Paul E.¹⁰¹¹¹²¹³,Abreu Monica¹⁴³⁴⁵¹⁵,Kiametis Alessandra Sofia¹⁴³⁴⁵¹⁵,Gargano Ricardo¹⁴³⁴⁵¹⁵^ORCID,Silveira Edilberto Rocha¹⁶¹⁷¹⁸¹⁵,Brand Guilherme D.¹⁹⁴⁵¹⁵,Prchal Lukas²⁰²¹²²,Soukup Ondřej²⁰²¹²²²³²⁴,Korábečný Jan²⁰²¹²²²³²⁴,Bolognesi Maria Laura⁶⁷⁸⁹,Soares Romeiro Luiz Antonio¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmacy

2. Health Sciences Faculty

3. University of Brasília

4. Campus Universitário Darcy Ribeiro

5. Brasília

6. Department of Pharmacy and Biotechnology

7. University of Bologna

8. 40126 Bologna

9. Italy

10. Tanz Centre for Research in Neurodegenerative Diseases and Dept. of Medical Biophysics

11. University of Toronto

12. M5T 2S8 Toronto

13. Canada

14. Physics Institute

15. Brazil

16. CENAUREMN, Department of Organic and Inorganic Chemistry

17. Federal University of Ceará

18. Fortaleza

19. Chemistry Institute, University of Brasília

20. Biomedical Research Centre

21. University Hospital Hradec Kralove

22. Czech Republic

23. Department of Toxicology and Military Pharmacy

24. Faculty of Military Health Sciences

Abstract

A series of cardanol derivatives has been developed from an inexpensive food waste material (i.e., cashew nut shell liquid, CNSL) to generate cholinesterase inhibitors with concomitant anti-amyloid and anti-oxidative activities and no cytotoxicity.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MD/D1MD00046B

Reference49 articles.

1. C.Brayne and B.Miller , Dementia and aging populations—A global priority for contextualized research and health policy , Public Library of Science San Francisco , CA USA , 2017

2. Alzheimer's Dementia , 2020 , 16 , 391–460

3. Reconsideration of Anticholinesterase Therapeutic Strategies against Alzheimer’s Disease

4. New potential AChE inhibitor candidates

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