Compounded topographical and physicochemical cueing by micro-engineered chitosan substrates on rat dorsal root ganglion neurons and human mesenchymal stem cells-Reference-Cited by-同舟云学术

Compounded topographical and physicochemical cueing by micro-engineered chitosan substrates on rat dorsal root ganglion neurons and human mesenchymal stem cells

Published:2021 Issue: Volume: Page:
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Lomboni David J.¹²³⁴⁵^ORCID,Steeves Alexander¹²³⁴⁵^ORCID,Schock Sarah⁶⁷⁸⁷,Bonetti Lorenzo⁹¹⁰¹¹¹²^ORCID,De Nardo Luigi⁹¹⁰¹¹¹²,Variola Fabio¹²³⁴⁵^ORCID

Affiliation:

1. Department of Mechanical Engineering

2. University of Ottawa

3. K1N 6N5 Canada

4. Ottawa-Carleton Institute for Biomedical Engineering (OCIBME)

5. Ottawa

6. Department of Cellular and Molecular Medicine, University of Ottawa

7. Canada

8. The Children's Hospital of Eastern Ontario (CHEO) Research Institute

9. Department of Chemistry

10. Materials and Chemical Engineering, “G. Natta”

11. Politecnico di Milano

12. Italy

Abstract

In this study, micro-engineered chitosan substrates were employed to investigate the compounded effects of topography, roughness and stiffness on the response of DRGs and hMSCs.

Funder

Natural Sciences and Engineering Research Council of Canada

Regione Lombardia

Ministry of Research and Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SM/D0SM02170A

Reference122 articles.

1. Biofabrication for neural tissue engineering applications