A screening method for the quantitative determination of selective androgen receptor modulators (SARMs) in capsules by high resolution 19F- and 1H-NMR spectroscopy

Author:

Maccelli Alessandro1ORCID,Borioni Anna1ORCID,Aureli Federica1ORCID,Gaudiano Maria Cristina1ORCID,Manna Livia1ORCID,Raimondo Mariangela1ORCID

Affiliation:

1. Chemical Medicines Unit, National Centre for the Control and Evaluation of Medicines, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Roma, Italy

Abstract

A new method for rapid determination of selective androgenic receptor modulators (SARMs) andarine, cardarine, ligandrol, ostarine and S-23 in capsules by 1H- and 19F-high resolution NMR spectroscopy was described and validated.

Publisher

Royal Society of Chemistry (RSC)

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