Development of a fluorescent probe library enabling efficient screening of tumour-imaging probes based on discovery of biomarker enzymatic activities-Reference-Cited by-同舟云学术

Development of a fluorescent probe library enabling efficient screening of tumour-imaging probes based on discovery of biomarker enzymatic activities

Published:2022 Issue:16 Volume:13 Page:4474-4481
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kuriki Yugo¹,Yoshioka Takafusa²³,Kamiya Mako²^ORCID,Komatsu Toru¹^ORCID,Takamaru Hiroyuki⁴,Fujita Kyohhei²,Iwaki Hirohisa²,Nanjo Aika¹,Akagi Yuki⁵,Takeshita Kohei²^ORCID,Hino Haruaki²³^ORCID,Hino Rumi⁶^ORCID,Kojima Ryosuke²⁷^ORCID,Ueno Tasuku¹^ORCID,Hanaoka Kenjiro¹^ORCID,Abe Seiichiro⁴^ORCID,Saito Yutaka⁴^ORCID,Nakajima Jun³^ORCID,Urano Yasuteru¹²⁸^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan

2. Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan

3. Department of Thoracic Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan

4. Endoscopy Division, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, Japan

5. Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, Japan

6. Daito Bunka University, Department of Sports and Health Science, 560, Iwadono, Higashimatsuyama, Saitama, Japan

7. PRESTO, Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi-shi, Saitama, Japan

8. CREST, Agency for Medical Research and Development (AMED), 1-7-1 Otemachi, Chiyoda-ku, Tokyo, Japan

Abstract

Efficient methodology to develop tumor-imaging fluorescent probes based on screening with our newly constructed probe library for aminopeptidase/protease (380 probes) and clinical samples has been established.

Funder

Japan Foundation for Applied Enzymology

Japan Agency for Medical Research and Development

Japan Science and Technology Agency

Naito Foundation

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC06889J