Induced conformational change on ferrocenyl-terminated alkyls and their application as transducers for label-free immunosensing of Alzheimer's disease biomarker-Reference-Cited by-同舟云学术

Induced conformational change on ferrocenyl-terminated alkyls and their application as transducers for label-free immunosensing of Alzheimer's disease biomarker

Published:2016 Issue:3 Volume:6 Page:2414-2421
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mars Abdelmoneim¹²³⁴⁵,Argoubi Wicem¹²³⁴⁵,Ben Aoun Sami⁶⁷⁸⁹¹⁰^ORCID,Raouafi Noureddine¹²³⁴⁵

Affiliation:

1. University of Tunis El-Manar

2. Faculty of Science of Tunis

3. Chemistry Department

4. Laboratory of Analytical Chemistry and Electrochemistry (LR99ES15)

5. Campus Universitaire de Tunis El-Manar 2092

6. Taibah University

7. Faculty of Science

8. Department of Chemistry

9. Al-Madinah Al-Munawarah

10. Saudi Arabia

Abstract

ApoE Alzheimer's disease biomarker can be sensitively detected by a label-free platform using flexible ferrocene-terminated alkyl chains. The immunorecognition triggers conformational changes, which improve the rate constants of electron-transfer.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA19328A

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