Thermodynamics, functional and structural characterization of inosine–uridine nucleoside hydrolase from Leishmania braziliensis-Reference-Cited by-同舟云学术

Thermodynamics, functional and structural characterization of inosine–uridine nucleoside hydrolase from Leishmania braziliensis

Published:2017 Issue:77 Volume:7 Page:48861-48875
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Dalberto Pedro Ferrari¹²³⁴,Martinelli Leonardo Kras Borges¹²³⁴,Bachega Jose Fernando Ruggiero⁵²³⁴,Timmers Luis Fernando Saraiva Macedo⁵²³⁴,Pinto Antonio Frederico Michel¹²³⁴,Dadda Adilio da Silva¹²³⁴,Petersen Guilherme Oliveira¹²³⁴,Subtil Fernanda Teixeira¹²³⁴,Galina Luiza¹²³⁴,Villela Anne Drumond¹²³⁴,Pissinate Kenia¹²³⁴,Machado Pablo¹²³⁴,Bizarro Cristiano Valim¹²³⁴,de Souza Osmar Norberto⁵²³⁴,de Carvalho Filho Edgar Marcelino⁶⁷⁸⁴,Basso Luiz Augusto¹²³⁴^ORCID,Santos Diogenes Santiago¹²³⁴

Affiliation:

1. Centro de Pesquisas em Biologia Molecular e Funcional (CPBMF)

2. Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)

3. Porto Alegre 90650-001

4. Brazil

5. Laboratório de Bioinformática, Modelagem e Simulação de Biossistemas (LABIO)

6. Hospital Universitário Professor Edgard Santos

7. Universidade Federal da Bahia

8. Salvador 40110160

Abstract

Inosine–uridine nucleoside hydrolase fromLeishmania braziliensisis a nonspecific enzyme that contains a disulfide bond not needed for tetramer stabilization.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

CAPES

FAPERGS

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA07268F

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