Water opens the door to organolithiums and Grignard reagents: exploring and comparing the reactivity of highly polar organometallic compounds in unconventional reaction media towards the synthesis of tetrahydrofurans-Reference-Cited by-同舟云学术

Water opens the door to organolithiums and Grignard reagents: exploring and comparing the reactivity of highly polar organometallic compounds in unconventional reaction media towards the synthesis of tetrahydrofurans

Published:2016 Issue:2 Volume:7 Page:1192-1199
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Cicco Luciana¹²³⁴⁵^ORCID,Sblendorio Stefania¹²³⁴⁵^ORCID,Mansueto Rosmara¹²³⁴⁵,Perna Filippo M.¹²³⁴⁵^ORCID,Salomone Antonio¹²³⁴⁵,Florio Saverio¹²³⁴⁵,Capriati Vito¹²³⁴⁵^ORCID

Affiliation:

1. Dipartimento di Farmacia-Scienze del Farmaco

2. Università di Bari “Aldo Moro”

3. Consorzio C.I.N.M.P.I.S.

4. Bari

5. Italy

Abstract

Grignard and organolithium reagents undergo smooth nucleophilic additions to γ-chloroketones “on water”.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC03436A

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