Synthesis of a DOTA-C-glyco bifunctional chelating agent and preliminary in vitro and in vivo study of [68Ga]Ga-DOTA-C-glyco-RGD-Reference-Cited by-同舟云学术

Synthesis of a DOTA-C-glyco bifunctional chelating agent and preliminary in vitro and in vivo study of [68Ga]Ga-DOTA-C-glyco-RGD

Published:2021 Issue:13 Volume:11 Page:7672-7681
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mangin Floriane¹²³⁴⁵,Collet Charlotte⁶⁷⁸¹⁹^ORCID,Jouan-Hureaux Valérie¹²¹⁰¹¹⁵,Maskali Fatiha⁶⁷⁸¹⁹,Roeder Emilie⁶⁷⁸¹⁹,Pierson Julien¹²¹⁰¹¹⁵,Selmeczi Katalin¹²³⁴⁵^ORCID,Marie Pierre-Yves⁶⁷⁸¹⁹,Boura Cédric¹²¹⁰¹¹⁵,Pellegrini-Moïse Nadia¹²³⁴⁵^ORCID,Lamandé-Langle Sandrine¹²³⁴⁵^ORCID

Affiliation:

1. Université de Lorraine

2. CNRS

3. L2CM

4. F-5400 Nancy

5. France

6. NancycloTEP

7. Molecular Imaging Platform

8. CHRU-Nancy

9. Nancy

10. CRAN

11. F-54000 Nancy

Abstract

A carbohydrate containing [⁶⁸Ga]Ga-DOTA-RGD tracer was designed and demonstrated promising results for cancer diagnosis by positron emission tomography imaging.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA09274F

Reference46 articles.

1. Bioconjugates of Chelators with Peptides and Proteins in Nuclear Medicine: Historical Importance, Current Innovations, and Future Challenges

2. Peptide Therapeutics and the Pharmaceutical Industry: Barriers Encountered Translating from the Laboratory to Patients

3. An Overview of Bioactive Peptides for in vivo Imaging and Therapy in Human Diseases

4. C-glyco“RGD” as αIIbβ3 and αvβ integrin ligands for imaging applications: Synthesis, in vitro evaluation and molecular modeling

5. Fully automated radiosynthesis of [18F]fluoro-C-glyco-c(RGDfC): exploiting all the abilities of the AllInOne synthesizer

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