Synthesis of pharmaceutically relevant 17-α-amino steroids using an ω-transaminase

Author:

Richter Nina12345,Simon Robert C.167,Kroutil Wolfgang45671,Ward John M.823,Hailes Helen C.123

Affiliation:

1. Department of Chemistry

2. University College London

3. London, UK

4. ACIB GmbH

5. c/o Department of Chemistry

6. University of Graz

7. 8010 Graz, Austria

8. Department of Biochemical Engineering

Abstract

An efficient and stereoselective biocatalytic route for the synthesis of 17α-amino steroids has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference32 articles.

1. Role of a Disordered Steroid Metabolome in the Elucidation of Sterol and Steroid Biosynthesis

2. Enantioselective synthesis of steroids

3. D. J. Mack , M. L.Weinrich , E.Vitaku and J. T.Njardarson , Top 200 Brand Name Drugs by US Retail Sales in 2010, http://cbc.arizona.edu/njardarson/group/top-pharmaceuticals-poster

4. Steroid sulfatase inhibitors: Promising new tools for breast cancer therapy?

5. Steroid sulfatase inhibitors: A review covering the promising 2000–2010 decade

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3