Synthesis of a novel hydrazone-based compound applied as a fluorescence turn-on chemosensor for iron(iii) and a colorimetric sensor for copper(ii) with antimicrobial, DFT and molecular docking studies

Author:

Rupa Sharmin Akther1,Patwary Md Abdul Majed1ORCID,Ghann William Emmanuel2,Abdullahi Adams2,Uddin A. K. M. Royhan1,Mahmud Md. Mayez3,Haque Md. Aminul4,Uddin Jamal2ORCID,Kazi Mohsin5

Affiliation:

1. Department of Chemistry, Comilla University, Cumilla-3506, Bangladesh

2. Center for Nanotechnology, Department of Natural Sciences, Coppin State University, Baltimore, USA

3. Tokushima University, Faculty of Pharmaceutical Science, Tokushima Shi 770-0026, Japan

4. Department of Chemistry, Jagannath University, Dhaka-1100, Bangladesh

5. Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia

Abstract

A novel molecule 5-bromo-2-hydroxy-N′-[(1E)-1-(thiophen-2-yl)ethylidene]benzohydrazide (L) has been designed and synthesized. The sensing studies of L showed a ratio metric & turn-on-enhanced fluorescence and colorimetric response toward Fe3+ and Cu2+ ions respectively.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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