Engineering of halohydrin dehalogenases for the regio- and stereoselective synthesis of (<i>S</i>)-4-aryl-2-oxazolidinones-Reference-Cited by-同舟云学术

Engineering of halohydrin dehalogenases for the regio- and stereoselective synthesis of (S)-4-aryl-2-oxazolidinones

Published:2024 Issue:7 Volume:14 Page:1967-1976
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Song Jinsong¹²,Zhou Chuanhua³,Chen Xi²^ORCID,Gu Yang¹,Xue Feng¹^ORCID,Wu Qiaqing²^ORCID,Zhu Dunming²^ORCID

Affiliation:

1. School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, No. 1, Wenyuan Road, Nanjing 210023, People's Republic of China

2. National Engineering Laboratory for Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China

3. Tianjin Changlu Haijing Group Co., Ltd., No. 1088, Yingkou Road, Tanggu, Binhai New Area, Tianjin, 300450, China

Abstract

Cyanate-mediated epoxide ring-opening by halohydrin dehalogenases (HHDHs) is a promising method for the synthesis of important optically pure 2-oxazolidinones.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CY/D3CY01584J

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