Application of paramagnetic graphene quantum dots as a platform for simultaneous dual-modality bioimaging and tumor-targeted drug delivery

Author:

Huang Chun-Lin1234,Huang Chih-Ching5674,Mai Fu-Der8910114,Yen Chia-Liang1213144,Tzing Shin-Hwa1234,Hsieh Hsiao-Ting8910114,Ling Yong-Chien1213144,Chang Jia-Yaw1234

Affiliation:

1. Department of Chemical Engineering

2. National Taiwan University of Science and Technology

3. Taipei 10607

4. Republic of China

5. Institute of Bioscience and Biotechnology and Center for Marine Bioenvironment and Biotechnology

6. National Taiwan Ocean UniVersity

7. Keelung

8. Department of Biochemistry

9. School of Medicine

10. Taipei Medical University

11. Taipei

12. Department of Chemistry

13. National Tsing Hua University

14. Hsinchu

Abstract

This paper reports the development of a multifunctional nanocarrier platform consisting of paramagnetic graphene quantum dots, folate, and doxorubicin for simultaneous fluorescence and MR imaging, and cancer treatment.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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