Unveiling structural and energetic characterization of the emissive RNA alphabet anchored in the methylthieno[3,4-<i>d</i>]pyrimidine heterocycle core-Reference-Cited by-同舟云学术

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Unveiling structural and energetic characterization of the emissive RNA alphabet anchored in the methylthieno[3,4-d]pyrimidine heterocycle core

Published:2024 Issue:22 Volume:26 Page:16358-16368
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Chawla Mohit¹^ORCID,Poater Albert²^ORCID,Oliva Romina³,Cavallo Luigi¹^ORCID

Affiliation:

1. King Abdullah University of Science and Technology (KAUST), Physical Sciences and Engineering Division, KAUST Catalysis Center, Thuwal 23955-6900, Saudi Arabia

2. Institut de Química Computacional i Catàlisi and Departament de Química, Universitat de Girona, c/Ma Aurèlia Capmany 69, Girona 17003, Catalonia, Spain

3. Department of Sciences and Technologies, University Parthenope of Naples, Centro Direzionale Isola C4, Naples, I-80143, Italy

Abstract

This study presents a comprehensive theoretical exploration of the fluorescent non-natural emissive nucleobases- mthA, mthG, mthC, and mthU derived from the methylthieno[3,4-d]pyrimidine heterocycle.

Funder

Generalitat de Catalunya

Ministerio de Ciencia e Innovación

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CP/D3CP06136A

Reference85 articles.

1. Synthetic biology

2. Synthesizing life

3. Monitoring Translation with Modified mRNAs Strategically Labeled with Isomorphic Fluorescent Guanosine Mimetics

4. A Highly Emissive Fluorescent Nucleoside that Signals the Activity of Toxic Ribosome-Inactivating Proteins

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