Pt(<scp>ii</scp>) metallacycles encapsulated by ferritin enable precise cancer combination chemo-photodynamic therapy-Reference-Cited by-同舟云学术

Pt(ii) metallacycles encapsulated by ferritin enable precise cancer combination chemo-photodynamic therapy

Published:2023 Issue:5 Volume:11 Page:1090-1099
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Min‡ Xuehong¹,Li‡ Ming²,Zhang‡ Wenjing²,Li Run-Hao³,Zhang Zhe⁴,Wang Pingshan⁴,Su Weide²,Li Feng²,Sun Yue³^ORCID,Liu Yi³^ORCID

Affiliation:

1. Wuhan Business University, Wuhan 430056, P. R. China

2. State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan 430071, P. R. China

3. Key State Key Laboratory of Separation Membrane and Membrane Process & Tianjin Key Laboratory of Green Chemical Technology and Process Engineering, School of Chemistry, Tiangong University, Tianjin 300387, P. R. China

4. Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, Guangzhou University, Guangzhou 510006, P. R. China

Abstract

We developed a multi-therapeutic organoplatinum-based drug (HFn-PtM) with good water solubility and active targeting via capturing metallacycles into the cavity of human heavy chain ferritin nanocages, which exhibited excellent anti-tumor efficiency.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Tianjin Science and Technology Program

Applied Fundamental Research of Wuhan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB02349K

Reference48 articles.