Exosome-mediated microRNA-497 delivery for anti-cancer therapy in a microfluidic 3D lung cancer model-Reference-Cited by-同舟云学术

Exosome-mediated microRNA-497 delivery for anti-cancer therapy in a microfluidic 3D lung cancer model

Published:2020 Issue:3 Volume:20 Page:548-557
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Jeong Kyeongsoo¹²³⁴,Yu Yeong Jun⁵⁶⁴,You Jae Young¹²³⁴,Rhee Won Jong¹²³⁴⁷^ORCID,Kim Jeong Ah⁵⁶⁴⁸⁹^ORCID

Affiliation:

1. Department of Bioengineering and Nano-Bioengineering

2. Incheon National University

3. Incheon 22012

4. Republic of Korea

5. Research Center for Bioconvergence Analysis

6. Korea Basic Science Institute

7. Division of Bioengineering

8. Department of Bio-Analytical Science

9. University of Science and Technology

Abstract

A 3D cell culture system that mimics the lung cancer microenvironment was used to investigate the effect of exosomes encapsulating miR-497 on tumor growth and angiogenesis, and could be a predictive, cost-efficient translational tool to develop targeted cancer therapy.

Funder

National Research Foundation of Korea

Korea Basic Science Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00958B

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1. MicroRNA signatures in human cancers

2. Integrated miRNA and mRNA expression profiling in response to eriodictyol in human endothelial cells