Mixed ligand copper(<scp>ii</scp>)-diimine complexes of 2-formylpyridine-N4-phenylthiosemicarbazone: diimine co-ligands tune thein vitronanomolar cytotoxicity-Reference-Cited by-同舟云学术

Mixed ligand copper(ii)-diimine complexes of 2-formylpyridine-N⁴-phenylthiosemicarbazone: diimine co-ligands tune thein vitronanomolar cytotoxicity

Published:2023 Issue:26 Volume:52 Page:9148-9169
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Kartikeyan Radhakrishnan¹,Murugan Dhanashree²,Ajaykamal Tamilarasan³^ORCID,Varadhan Manikandan¹,Rangasamy Loganathan²,Velusamy Marappan⁴^ORCID,Palaniandavar Mallayan³^ORCID,Rajendiran Venugopal¹^ORCID

Affiliation:

1. Department of Chemistry, School of Basic and Applied Sciences, Central University of Tamil Nadu, Thiruvarur 610005, India

2. Drug Discovery Unit (DDU), Centre for Biomaterials, Cellular and Molecular Theranostics (CBCMT), Vellore Institute of Technology (VIT), Vellore 632014, Tamil Nadu, India

3. School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, India

4. Department of Chemistry, North Eastern Hill University, Shillong 793022, India

Abstract

The bpy (IC50, 7 nM) and 5,6-dmp (IC50,13.57 nM) Cu(ii) complexes exhibit phenomenal cytotoxicity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00213F

Reference134 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries