Optimization of a broth conductivity controlling strategy directed by an online viable biomass sensor for enhancing Taxus cell growth rate and Taxol productivity-Reference-Cited by-同舟云学术

Optimization of a broth conductivity controlling strategy directed by an online viable biomass sensor for enhancing Taxus cell growth rate and Taxol productivity

Published:2016 Issue:47 Volume:6 Page:40631-40640
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Ze-Jian¹²³⁴⁵,Zhang Wei¹²³⁴,Zhang Jian-Wen¹²³⁴,Guo Mei-Jin¹²³⁴,Zhuang Ying-ping¹²³⁴

Affiliation:

1. State Key Laboratory of Bioreactor Engineering

2. East China University of Science and Technology

3. Shanghai 200237

4. China

5. Department of Biotechnology

Abstract

In this work, we investigated the effects of a constant broth conductivity controlling strategy directed by an online viable biomass sensor on Taxol productivity ofTaxus chinensisvar.maireiin suspension cultivation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA26540A

Reference51 articles.

1. Optimization of the basal medium for improving production and secretion of taxanes from suspension cell culture of Taxus baccata L

2. Source of isopentenyl diphosphate for taxol and baccatin III biosynthesis in cell cultures of Taxus baccata

3. Production of the anticancer drug taxol in Taxus baccata suspension cultures: A review

4. Sustainable use of Taxus media cell cultures through minimal growth conservation and manipulation of genome methylation

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