Diastereoselective desymmetrization reactions of prochiral para-quinamines with cyclopropenes generated in situ: access to fused hydroindol-5-one scaffolds-Reference-Cited by-同舟云学术

Diastereoselective desymmetrization reactions of prochiral para-quinamines with cyclopropenes generated in situ: access to fused hydroindol-5-one scaffolds

Published:2021 Issue:33 Volume:19 Page:7129-7133
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lodhi Rajni¹,Prakash Meher¹,Samanta Sampak¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Indore, Simrol, 453552, India

Abstract

A base-promoted diastereoselective desymmetric [3 + 2] annulation reaction of prochiral para-quinamines with 2-aroyl-1-chlorocyclopropanecarboxylates to provide a series of fused-hydroindol-5-ones bearing four stereogenic centres is reported.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01322J

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