Copper(i)-catalyzed asymmetric intramolecular C-arylation with ureas as the additives: highly enantioselective formation of spirooxindoles-Reference-Cited by-同舟云学术

Copper(i)-catalyzed asymmetric intramolecular C-arylation with ureas as the additives: highly enantioselective formation of spirooxindoles

Published:2021 Issue:34 Volume:19 Page:7480-7484
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ma Haowen¹,Feng Jiajie²³,Zhou Wei¹^ORCID,Chen Chen¹,Deng Zhuoji¹,Zhou Fengtao¹,Ouyang Yifan¹,Zhang Xinhao²³^ORCID,Cai Qian¹^ORCID

Affiliation:

1. College of Pharmacy, Jinan University, No. 601 Huangpu Avenue West, Guangzhou, 510632, China

2. Lab of Computational Chemistry and Drug Design, State Key Laboratory of Chemical Oncogenomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China

3. Shenzhen Bay Laboratory, Shenzhen 518132, China

Abstract

A cooperative catalytic strategy is developed for a copper-catalyzed asymmetric intramolecular C-arylation reaction with ureas as the co-catalysts.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01327K

Reference58 articles.

1. CCXLIV.—Replacement of halogen in orthobromo-benzoic acid

2. I. P.Beletskaya and A. Y.Fedorov , Modern copper-catalyzed Hurtley reaction: efficient C-arylation of C-H acid, in: Copper-mediated cross-coupling reactions , ed. G. Evano and N. Blanchard , 2014 , John Wiley & Sons , pp. 281–312

3. Ullmann‐Ma Reaction: Development, Scope and Applications in Organic Synthesis †

4. Selected Copper-Based Reactions for C−N, C−O, C−S, and C−C Bond Formation

5. Copper catalysed Ullmann type chemistry: from mechanistic aspects to modern development