Mechanochemical Fischer indolisation: an eco-friendly design for a timeless reaction-Reference-Cited by-同舟云学术

Mechanochemical Fischer indolisation: an eco-friendly design for a timeless reaction

Published:2022 Issue:12 Volume:24 Page:4859-4869
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Porcheddu Andrea¹^ORCID,Mocci Rita¹^ORCID,Brindisi Margherita²^ORCID,Cuccu Federico¹^ORCID,Fattuoni Claudia¹^ORCID,Delogu Francesco³^ORCID,Colacino Evelina⁴^ORCID,D'Auria Maria Valeria²^ORCID

Affiliation:

1. Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Cittadella Universitaria, 09042 Cagliari, Italy

2. Dipartimento di Farmacia, Università degli Studi di Napoli ‘Federico II’, Via Domenico Montesano 49, 80131, Napoli, Italy

3. Dipartimento di Ingegneria Meccanica, Chimica, e dei Materiali, Università degli Studi di Cagliari, via Marengo 2, 09123 Cagliari, Italy

4. ICGM, Univ Montpellier CNRS, ENSCM, Montpellier, France

Abstract

We developed an environmentally friendly mechanochemical protocol to induce an effective Fischer indolisation to synthesize indoles and indolines taking advantage of oxalic acid and dimethylurea.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

European Cooperation in Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D2GC00724J

Reference94 articles.

1. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

2. A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications