Visible-light mediated carbonyl trifluoromethylative amination as a practical method for the synthesis of β-trifluoromethyl tertiary alkylamines
Author:
Affiliation:
1. Department of Chemistry
2. University of Cambridge
3. Cambridge
4. UK
Abstract
An operationally straightforward, visible-light-mediated multicomponent strategy for the construction of β-trifluoromethylated tertiary alkylamines from aldehydes, secondary amines and a convenient source of trifluoromethyl iodide is reported.
Funder
Royal Society
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC04853D
Reference45 articles.
1. Predicting and Tuning Physicochemical Properties in Lead Optimization: Amine Basicities
2. Cytochrome P450: Structure, mechanism, and biochemistry , ed. O. de Montellano and R. Paul , Springer , 2005
3. Fluorine in Pharmaceuticals: Looking Beyond Intuition
4. Fluorine in medicinal chemistry
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