A ratiometric fluorescent probe for in vivo tracking of alkaline phosphatase level variation resulting from drug-induced organ damage-Reference-Cited by-同舟云学术

A ratiometric fluorescent probe for in vivo tracking of alkaline phosphatase level variation resulting from drug-induced organ damage

Published:2015 Issue:6 Volume:3 Page:1042-1048
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Hou Xianfeng¹²³⁴⁵,Yu Qingxiang¹²³⁴⁵,Zeng Fang¹²³⁴⁵,Ye Junhui¹²³⁴⁵,Wu Shuizhu¹²³⁴⁵

Affiliation:

1. College of Materials Science and Engineering

2. State Key Laboratory of Luminescent Materials and Devices

3. South China University of Technology

4. Guangzhou 510640

5. China

Abstract

The ratiometric fluorescent probe discussed herein can detect ALP levels in clinical serum samples, and spatially map endogenous ALP level variations, which occur as a result of drug induced organ damage.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TB/C4TB01744G

Reference72 articles.

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4. The ELFR-97 phosphatase substrate provides a sensitive, photostable method for labelling cytological targets

5. Placental alkaline phosphatase isoenzyme in quality control materials may be a source of variability in alkaline phosphatase activity

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