A successful search for new, efficient, and silver-free manufacturing processes for key platinum(ii) intermediates applied in antibody–drug conjugate (ADC) production
Author:
Affiliation:
1. LinXis BV
2. De Boelelaan 1085c
3. The Netherlands
4. ChemConnection BV/Ardena Oss
5. Oss, 5349 AB
6. Department of Radiology and Nuclear Medicine
7. Amsterdam UMC
8. Location VU Medical Center
9. Amsterdam
Abstract
A silver-free amination procedure was developed to obtain an important class of Pt(II) complexes as direct precursors for antibody-drug conjugates.
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/GC/C9GC03130H
Reference29 articles.
1. The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
2. Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer
3. Inotuzumab Ozogamicin: First Global Approval
4. Recent Developments in ADC Technology: Preclinical Studies Signal Future Clinical Trends
5. An FDA oncology analysis of antibody-drug conjugates
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Antibody Drug Conjugates for Cancer Therapy: From Metallodrugs to Nature-Inspired Payloads;International Journal of Molecular Sciences;2024-08-08
2. Metal Complexes as the Means or the End of Targeted Delivery for Unmet Needs;Targeted Drug Delivery;2022-11-18
3. Nanoscale bioconjugates: A review of the structural attributes of drug-loaded nanocarrier conjugates for selective cancer therapy;Heliyon;2022-06
4. The Chemistry Behind ADCs;Pharmaceuticals;2021-05-07
5. An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt II Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates;Angewandte Chemie;2021-01-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3