Anti-angiogenic properties of chlorambucil derivatives with fluorous and hydrocarbon appendages-Reference-Cited by-同舟云学术

Anti-angiogenic properties of chlorambucil derivatives with fluorous and hydrocarbon appendages

Published:2016 Issue:8 Volume:7 Page:1596-1603
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Nowak-Sliwinska Patrycja¹²³⁴⁵,Weiss Andrea⁶⁷⁸⁹,Păunescu Emilia⁶⁷⁸⁹,Clavel Catherine M.⁶⁷⁸⁹,Griffioen Arjan W.¹²³⁴⁵,Dyson Paul J.¹⁰¹¹¹²⁹

Affiliation:

1. Angiogenesis Laboratory

2. Department of Medical Oncology

3. VU University Medical Center

4. Amsterdam

5. The Netherlands

6. School of Pharmaceutical Sciences

7. University of Geneva

8. CH-1211 Geneva 4

9. Switzerland

10. Institute of Chemical Sciences and Engineering

11. Swiss Federal Institute of Technology (EPFL)

12. Lausanne

Abstract

Chlorambucil (CLB) derivatives with long fluorous (referred to as 1 and 2) or hydrocarbon (3) chains have been evaluated in a series of in vitro and in vivo assays.

Funder

KWF Kankerbestrijding

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00271D

Reference37 articles.

1. Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): a randomised, multicentre, open-label phase 3 trial

2. Rituximab Plus Chlorambucil As First-Line Treatment for Chronic Lymphocytic Leukemia: Final Analysis of an Open-Label Phase II Study

3. A Reappraisal of the Role of Chlorambucil in Patients with End Stage Ovarian Cancer Who Have Previously been Treated with Platinum Regimens

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