Systemic and characteristic metabolites in the serum of streptozotocin-induced diabetic rats at different stages as revealed by a1H-NMR based metabonomic approach
Author:
Affiliation:
1. Department of Radiology
2. the first Affiliated Hospital
3. Wenzhou Medical University
4. Wenzhou 325000, PR China
5. Institute of Metabonomics & Pharmaceutical NMR
6. School of Pharmacy
7. Wenzhou 325035, PR China
Abstract
A schematic diagram of the disturbed metabolic pathways showing that glycolysis, the TCA cycle, glucogeogenesis andetc. are involved in the evolution of diabetes.
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2014/MB/C3MB70609E
Reference32 articles.
1. Global Prevalence of Diabetes
2. Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat
3. Metabonomics and diabetes mellitus
4. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
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