Second near-infrared photodynamic therapy and chemotherapy of orthotopic malignant glioblastoma with ultra-small Cu2−xSe nanoparticles

Author:

Zhang Hao12345,Wang Tingting12345,Liu Hanghang12345,Ren Feng12345,Qiu Weibao678910,Sun Qiao12345ORCID,Yan Fei678910,Zheng Hairong678910,Li Zhen12345ORCID,Gao Mingyuan12345ORCID

Affiliation:

1. Center for Molecular Imaging and Nuclear Medicine

2. State Key Laboratory of Radiation Medicine and Protection

3. School for Radiological and Interdisciplinary Sciences (RAD-X)

4. Soochow University

5. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

6. Paul C. Lauterbur Research Center for Biomedical Imaging

7. Institute of Biomedical and Health Engineering

8. Shenzhen Institutes of Advanced Technology

9. Chinese Academy of Sciences

10. Shenzhen 518055

Abstract

Herein we synthesize DOX-loaded ultra-small Cu2−xSe nanoparticles for the NIR-II photodynamic therapy and chemotherapy of orthotopic malignant glioblastoma.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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