Modelling methacrylated chitosan hydrogel properties through an experimental design approach: from composition to material properties

Author:

Bucciarelli Alessio1ORCID,Selicato Nora2,Coricciati Chiara23,Rainer Alberto24ORCID,Capodilupo Agostina Lina2ORCID,Gigli Giuseppe23,Moroni Lorenzo5ORCID,Polini Alessandro2ORCID,Gervaso Francesca2ORCID

Affiliation:

1. Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy

2. CNR NANOTEC – Institute of Nanotechnology, National Council of Research, University Campus Ecotekne, Via Monteroni, 73100 Lecce, Italy

3. Dipartimento di Matematica e Fisica E. de Giorgi, Università Del Salento, Campus Ecotekne, via Monteroni, 73100, Lecce, Italy

4. Department of Engineering, Università Campus Bio-Medico di Roma, via Alvaro del Portillo, 21, 00128, Rome, Italy

5. MERLN Institute for Technology-Inspired Regenerative Medicine, Complex Tissue Regeneration Department, Maastricht University, Universiteitssingel 40, 6229ER Maastricht, the Netherlands

Abstract

Methacrylated chitosan hydrogels properties are modelled using a statistical approach. The obtained empirical equations allow to fine tune the properties by changing the hydrogel composition and the fabrication variables.

Funder

Regione Puglia

Horizon 2020 Framework Programme

Ministero dell'Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

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