Photolysis of methicillin-resistant Staphylococcus aureus using Cu-doped carbon spheres

Author:

Xi Juqun12345,An Lanfang12345,Wei Gen12345,Huang Yaling12345,Li Dandan657,Fan Lei8497ORCID,Gao Lizeng101112137

Affiliation:

1. Institute of Translational Medicine

2. Department of Pharmacology

3. School of Medicine

4. Yangzhou University

5. Yangzhou 225001

6. Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases

7. China

8. School of Chemistry and Chemical Engineering

9. Yangzhou

10. CAS Engineering Laboratory for Nanozyme

11. Institute of Biophysis

12. Chinese Academy of Sciences

13. Beijing 100101

Abstract

Cu-HCSs in combination with blue-light irradiation promoted photobleaching of STX to destroy membrane integrity, and further caused oxidative cleavage of DNA and proteins inside MRSA, resulting in efficient killing of MRSA.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Yangzhou University

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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