Synthesis of pentasubstituted 2-aryl pyrroles from boryl and stannyl alkynes via one-pot sequential Ti-catalyzed [2 + 2 + 1] pyrrole synthesis/cross coupling reactions-Reference-Cited by-同舟云学术

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Synthesis of pentasubstituted 2-aryl pyrroles from boryl and stannyl alkynes via one-pot sequential Ti-catalyzed [2 + 2 + 1] pyrrole synthesis/cross coupling reactions

Published:2020 Issue:37 Volume:11 Page:10236-10242
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Cheng Yukun¹²³⁴^ORCID,Klein Channing K.¹²³⁴^ORCID,Tonks Ian A.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Minnesota – Twin Cities

3. Minneapolis

4. USA

Abstract

Multisubstituted pyrroles are commonly found in many bioactive small molecule scaffolds, yet the synthesis of highly-substituted pyrrole cores remains challenging.

Funder

National Institute of General Medical Sciences

Alfred P. Sloan Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01576H

Reference48 articles.

1. An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals

2. The biology and chemistry of antifungal agents: A review

3. Biological formation of pyrroles: Nature's logic and enzymatic machinery

4. Electrochemically synthesized polymers in molecular imprinting for chemical sensing

5. BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties

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1. Six-Membered Iridacycles with Five Nitrogen Atoms in the Ring;Organometallics;2024-07-01

2. Ti-Catalyzed Multicomponent Synthesis of Pyrroles Using Allene Coupling Partners;Organometallics;2023-06-23

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4. Zr vs. Ti molecular and silica-supported imido complexes in stoichiometric and catalytic oxo/imido heterometathesis;Inorganic Chemistry Frontiers;2023

5. Synthesis of Pyrrole via Formal Cycloaddition of Allyl Ketone and Amine under Metal-Free Conditions;The Journal of Organic Chemistry;2022-09-02

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