Technetium-99m and rhenium-188 complexes with one and two pendant bisphosphonate groups for imaging arterial calcification
Author:
Affiliation:
1. King's College London
2. Division of Imaging Sciences and Biomedical Engineering
3. St Thomas’ Hospital
4. London SE1 7EH
5. UK
6. Cardiovascular Division
7. James Black Centre
8. London SE5 9NU
Abstract
The synthesis of the first technetium-99m and rhenium-188 complexes with two pendant bisphosphonate groups is described, along with their in vivo use in imaging the skeleton and arterial calcification.
Funder
Wellcome Trust
British Heart Foundation
National Institute for Health Research
Cancer Research UK
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT02965H
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1. ‘Magic bullets’ for bone diseases: progress in rational design of bone-seeking medicinal agents
2. Comparison of various rhenium-188-labeled diphosphonates for the treatment of bone metastases
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