Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin-Reference-Cited by-同舟云学术

Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin

Published:2016 Issue:10 Volume:12 Page:3132-3138
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

del Gaudio Federica¹²³⁴⁵,Festa Carmen¹⁶⁷⁸⁴,Mozzicafreddo Matteo⁹¹⁰¹¹⁴^ORCID,Vasaturo Michele¹²³⁴,Casapullo Agostino¹²³⁴,De Marino Simona¹⁶⁷⁸⁴,Riccio Raffaele¹²³⁴,Monti Maria Chiara¹²³⁴

Affiliation:

1. Department of Pharmacy

2. University of Salerno

3. Fisciano

4. Italy

5. PhD Program in Drug Discovery and Development

6. University of Naples “Federico II”

7. Via D. Montesano

8. I-80131 Naples

9. School of Biosciences and Veterinary Medicine

10. University of Camerino

11. 62032 Camerino

Abstract

Extracts ofRuscus aculeatusare rich of deglucoruscin, a spirostanol glycoside, which is able to interact with ATP synthase and modulate its activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MB/C6MB00460A

Reference32 articles.

1. Spirostanol saponins and esculin from Rusci rhizoma reduce the thrombin-induced hyperpermeability of endothelial cells

2. Effects of Ruscus Extract on the Internal Diameter of Arterioles and Venules of the Hamster Cheek Pouch Microcirculation

3. Steroidal saponins from the underground parts of Ruscus aculeatus and their cytostatic activity on HL-60 cells

4. Anti-Elastase and Anti-Hyaluronidase Activities of Saponins and Sapogenins fromHedera helix, Aesculus hippocastanum, andRuscus aculeatus: Factors Contributing to their Efficacy in the Treatment of Venous Insufficiency

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