Synthesis and anti-proliferative activity evaluation of novel 1,4-naphthoquinones possessing pyrido[2,3-d]pyrimidine scaffolds-Reference-Cited by-同舟云学术

Synthesis and anti-proliferative activity evaluation of novel 1,4-naphthoquinones possessing pyrido[2,3-d]pyrimidine scaffolds

Published:2016 Issue:78 Volume:6 Page:73953-73958
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Chong¹²³⁴,Sun Guangfei¹²³⁴,Peng Qiujv¹²³⁴,Zhu Shiwei¹²³⁴,Ni Dongxuan¹²³⁴

Affiliation:

1. School of Pharmacy

2. Xinxiang Medical University

3. Xinxiang 453003

4. China

Abstract

A series of novel 1,4-naphthoquinones possessing pyrido[2,3-d]pyrimidine scaffolds were synthesized and most of the compounds exhibited excellent anti-proliferative activities.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA17032C

Reference24 articles.

1. Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry

2. Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents

3. Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold

4. Cytotoxicity of new n-butylamino and sulfur-containing derivatives of polyfluorinated 1,4-naphthoquinone

5. Synthesis and evaluation of antifungal activity of naphthoquinone derivatives

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