N-Heterocyclic carbene (NHC)-catalyzed intramolecular benzoin condensation

N-Heterocyclic carbene (NHC)-catalyzed intramolecular benzoin condensation–oxidation

Published:2021 Issue:7 Volume:19 Page:1488-1492
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Satyam Killari¹²³⁴⁵,Ramarao Jakkula¹²³⁴⁵,Suresh Surisetti¹²³⁴⁵^ORCID

Affiliation:

1. Department of Organic Synthesis and Process Chemistry

2. CSIR-Indian Institute of Chemical Technology (CSIR-IICT)

3. Hyderabad 500 007

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

NHC-Catalyzed intramolecular benzoin condensation–oxidation has been disclosed for the expedient synthesis of diverse seven-membered heterocyclic 1,2-diketones in good to excellent yields, under ambient conditions.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02606A

Reference52 articles.

1. An overview of N-heterocyclic carbenes

2. Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

3. Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

4. Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

5. N-Heterocyclic carbenes in organocatalysis , ed. A. T. Biju , Wiley-VCH , Weinheim , 2019

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 1,2-Amidoarylcarbonylation of Styrenes to Access β-Acylamino Ketones by NHC-Catalyzed Radical Relay;The Journal of Organic Chemistry;2024-08-28

2. Synthesis and Characterization of New Bulky α‐Hydroxy Ketones by N‐Heterocyclic Carbene‐Catalyzed Intramolecular Benzoin Condensation;ChemistrySelect;2024-07-04

3. Drastically Accelerated Radical Recombination Kinetics of a Hexaarylbiimidazole Derivative;The Journal of Physical Chemistry Letters;2024-06-05

4. Highly Efficient N‐Heterocyclic Carbene Precursor from Sterically Hindered Benzimidazolium Salt for Benzoin Condensation;ChemistrySelect;2024-04-25

5. NHC-Catalyzed Formal [4 + 2] Annulation of o-Formyl-Tethered Michael Acceptors and Ynones to Access Highly Functionalized Naphthalene Derivatives;Organic Letters;2024-02-27