Uncovering the structures of modular polyketide synthases-Reference-Cited by-同舟云学术

Uncovering the structures of modular polyketide synthases

Published:2015 Issue:3 Volume:32 Page:436-453
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Weissman Kira J.¹²³⁴⁵

Affiliation:

1. Molecular and Structural Enzymology Group

2. Université de Lorraine

3. IMoPA

4. UMR 7365

5. Vandœuvre-lès-Nancy

Abstract

This review covers a breakthrough in the structural biology of the gigantic modular polyketide synthases (PKS): the structural characterization of intact modules by single-particle cryo-electron microscopy and small-angle X-ray scattering.

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NP/C4NP00098F

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