Digital microfluidics with distance-based detection – a new approach for nucleic acid diagnostics-Reference-Cited by-同舟云学术

Digital microfluidics with distance-based detection – a new approach for nucleic acid diagnostics

Published:2024 Issue:1 Volume:24 Page:63-73
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ho Man¹²,Sathishkumar N.¹²^ORCID,Sklavounos Alexandros A.¹²^ORCID,Sun Jianxian¹,Yang Ivy³,Nichols Kevin P.⁴,Wheeler Aaron R.¹²⁵^ORCID

Affiliation:

1. Department of Chemistry, University of Toronto, 80. St. George Street, Toronto, Ontario, M5S 3H6, Canada

2. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario, M5S 3E1, Canada

3. Department of Chemical Engineering & Applied Chemistry, University of Toronto, 200 College Street, Toronto, Ontario, M5S 3E5, Canada

4. Global Health Labs, Bellevue, WA, 98007, USA

5. Institute of Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada

Abstract

We introduce the integration of digital microfluidics (DMF) with distance-based detection (DBD). This platform allows for miniaturized diagnosis of infectious diseases in a format that is easy to operate with a detection scheme that can be read by eye.

Funder

National Research Council Canada

Natural Sciences and Engineering Research Council of Canada

University of Toronto

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2024/LC/D3LC00683B

Reference55 articles.

1. Advances in nucleic acid amplification techniques (NAATs): COVID-19 point-of-care diagnostics as an example