Chemically triggered release of 5-aminolevulinic acid from liposomes-Reference-Cited by-同舟云学术

Chemically triggered release of 5-aminolevulinic acid from liposomes

Published:2014 Issue:101 Volume:4 Page:57983-57990
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Plaunt Adam J.¹²³,Harmatys Kara M.¹²³,Hendrie Kyle A.¹²³,Musso Anthony J.¹²³,Smith Bradley D.¹²³

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of Notre Dame

3. Notre Dame, USA

Abstract

A zinc(ii)-dipicolylamine coordination complex acts as a chemical trigger to release 5-ALA from stealth liposomes and allows uptake into neighboring mammalian cells for conversion into fluorescent PpIX.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA10340H

Reference33 articles.

1. Aminolevulinic acid (ALA): photodynamic detection and potential therapeutic applications

2. Protoporphyrin IX Level Correlates with Number of Mitochondria, But Increase in Production Correlates with Tumor Cell Size

3. Cell-type Specific Protoporphyrin IX Metabolism in Human Bladder Cancer in vitro¶

4. Use of fluorescence to guide resection or biopsy of primary brain tumors and brain metastases

5. Photodynamic therapy of malignant brain tumours: A complementary approach to conventional therapies

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