Microscopic significance of hydrophobic residues in the protein-stabilizing effect of trimethylamine N-oxide (TMAO)-Reference-Cited by-同舟云学术

Microscopic significance of hydrophobic residues in the protein-stabilizing effect of trimethylamine N-oxide (TMAO)

Published:2016 Issue:32 Volume:18 Page:22081-22088
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Yang Yanmei¹²³⁴,Mu Yuguang⁵⁶⁷,Li Weifeng¹²³⁴

Affiliation:

1. School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

2. Soochow University

3. Suzhou

4. China

5. School of Biological Sciences

6. Nanyang Technological University

7. Singapore

Abstract

Proteins with a higher hydrophobic content are better protected by TMAO against the deleterious effect of urea.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CP/C6CP01205A

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