The role of an active site Mg2+ in HDV ribozyme self-cleavage: insights from QM/MM calculations-Reference-Cited by-同舟云学术

The role of an active site Mg2+ in HDV ribozyme self-cleavage: insights from QM/MM calculations

Author:

Mlýnský Vojtěch¹²³⁴⁵,Walter Nils G.⁶⁷⁸⁹¹⁰,Šponer Jiří¹¹¹²¹³¹⁴¹⁵,Otyepka Michal¹²³⁴⁵,Banáš Pavel¹²³⁴⁵

Affiliation:

1. Regional Centre of Advanced Technologies and Materials

2. Department of Physical Chemistry

3. Faculty of Science

4. Palacky University

5. Olomouc

6. Department of Chemistry

7. Single Molecule Analysis Group

8. University of Michigan

9. 930 North University Avenue

10. Ann Arbor

11. Institute of Biophysics

12. Academy of Sciences of the Czech Republic

13. 612 65 Brno

14. Czech Republic

15. CEITEC – Central European Institute of Technology

Abstract

The specific position and coordination of active site Mg²⁺ ion have a significant direct impact on the self-cleavage reaction in HDV ribozyme.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

Reference57 articles.

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