Lactoferrin modulates gut microbiota and Toll-like receptors (TLRs) in mice with dysbiosis induced by antibiotics

Author:

Bellés Andrea12ORCID,Aguirre-Ramírez Diego1,Abad Inés23,Parras-Moltó Marcos4567,Sánchez Lourdes23,Grasa Laura128ORCID

Affiliation:

1. Universidad de Zaragoza, Facultad de Veterinaria, Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Zaragoza, Spain

2. Instituto Agroalimentario de Aragón IA2 (UNIZAR-CITA), Zaragoza, Spain

3. Universidad de Zaragoza, Facultad de Veterinaria, Departamento de Producción Animal y Tecnología de los Alimentos, Zaragoza, Spain

4. Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Gothenburg, Sweden

5. Centre for Antibiotic Resistance Research, University of Gothenburg, Gothenburg, Sweden

6. Igenomix Foundation/INCLIVA Biomedical Research Institute, Spain

7. Department of Science, Universidad Internacional de Valencia-VIU, Valencia, Spain

8. Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain

Abstract

In situations of intestinal dysbiosis caused by taking antibiotics, lactoferrin, a bovine milk protein, improves intestinal health by modulating the intestinal microbiota and the immune system positively and can be used in functional foods.

Funder

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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