Preparation of a novel regenerated silk fibroin-based hydrogel for extrusion bioprinting

Author:

Chen Ni1,Zhang Xinbo2,Lyu Jinyang3,Zhao Guanglei3,Gu Kai1ORCID,Xia Jun3,Chen Zhongchun4,Shao Zhengzhong1ORCID

Affiliation:

1. State Key Laboratory of Molecular Engineering of Polymers, Laboratory of Advanced Materials and Department of Macromolecular Science, Fudan University, Shanghai 200433, P. R. China

2. Department of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, P. R. China

3. Department of Orthopedic Surgery, Huashan Hospital, Fudan University, Shanghai 200040, P. R. China

4. Department of Otorhinolaryngology-Head and Neck Surgery, Huashan Hospital, Fudan University, Shanghai 200040, P. R. China

Abstract

A bio-printable hydrogel of regenerated silk fibroin with high-molecular-weight was prepared from its aqueous solution with the help of urea involvement, and the gelation process and properties of the hydrogel was investigated.

Funder

National Science and Technology Major Project

Shanghai Municipal Health Commission

Natural Science Foundation of Shanghai

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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