Fast and reliable ICP-MS quantification of palladium and platinum-based drugs in animal pharmacokinetic and biodistribution studies-Reference-Cited by-同舟云学术

Fast and reliable ICP-MS quantification of palladium and platinum-based drugs in animal pharmacokinetic and biodistribution studies

Published:2020 Issue:39 Volume:12 Page:4806-4812
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Vojtek Martin¹²³⁴⁵^ORCID,Pinto Edgar¹⁶⁷⁴⁵^ORCID,Gonçalves-Monteiro Salomé¹²³⁴⁵,Almeida Agostinho¹⁸⁷⁴⁵,Marques M. P. M.⁹¹⁰¹¹¹²¹³^ORCID,Mota-Filipe Helder¹⁴⁴¹⁵¹⁶¹³^ORCID,Ferreira Isabel M. P. L. V. O.¹⁶⁷⁴⁵^ORCID,Diniz Carmen¹²³⁴⁵^ORCID

Affiliation:

1. LAQV/REQUIMTE

2. Laboratory of Pharmacology

3. Department of Drug Sciences

4. Faculty of Pharmacy

5. University of Porto

6. Laboratory of Bromatology and Hydrology

7. Department of Chemical Sciences

8. Laboratory of Applied Chemistry

9. Unidade de I&D “Química-Física Molecular”

10. Department of Chemistry

11. University of Coimbra

12. 3004-535 Coimbra

13. Portugal

14. iMed.ULisboa

15. University of Lisbon

16. 1649-003 Lisbon

Abstract

The paper describes validated micro-method suitable for quantitative analysis of palladium- and platinum-based anticancer drugs in 11 distinct animal tissues/biofluids obtained from multi-organ pharmacokinetic/biodistribution animal studies.

Funder

Fundação para a Ciência e a Tecnologia

Programa Operacional Temático Factores de Competitividade

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AY/D0AY01328E

Reference17 articles.

1. Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects